Robarts Research

Stroke Prevention Research
Dr. J. David Spence
&
Dr. Daniel Hackam

Current Research Projects


Stroke Prevention & Atherosclerosis Research Centre
Current (C) and Recent (R) Studies
Sponsor
Study Name
Peer-Reviewed
HSFO* R Imaging for appropriate endarterectomy
HSFO R Linkage studies: London genotyping project
HSFO C Linkage studies: Chicoutimi phenotyping project
HSFO C Biomarkers in carotid atherosclerosis
HSFO C Ultrasound phenotypes and cardiovascular risk
CIHR* C Canadian Atherosclerosis Imaging Network
CIHR C Diabetic intervention with vitamins to improve nephropathy (DIVINe)
CIHR C Thyroxine and carotid plaque progression in subclinical hypothyroidism
NIH* C Siblings with Ischemic Stroke (SWISS)
NIH R Vitamin Intervention for Stroke Prevention (VISP) trial
NIH C Insulin resistance for Ischemic Stroke (IRIS)
NIH C WARCEF Anticoagulation in patients with low ejection fraction
Contracts
Wyeth R Policosanol vs. placebo to lower LDL
Pfizer R TCD Atorvastatin and carotid plaque volume
NMT C CLOSURE - PFO study
Pfizer R SPARCL Atorvastatin in stroke patients
Sanofi R MATCH clopidogrel ± ASA in TIA
Pan American C DIVINe substudy: carotid plaque progression
Boehringer
Ingelheim
C PRoFESS placebo controlled study of aggrenox vs. clopidogrel, with & without telmisartan
Sanofi R CHARISMA ASA ± clopidogrel in stroke prevention
Takeda C Squalene synthase inhibitor plus rosuvastatin
Glaxo
SmithKline
C Effect of rosiglitazone on carotid plaque progression
Wyeth C Immunosuppressives and carotid plaque progression
Servier C PERFORM terutroban vs ASA in stroke prevention
Sanofi-Aventis C CRESCENDO rimonabant for insulin resistance
Activbiotics C Effect of antibiotic therapy for Chlamydia Pneumoniae on carotid atherosclerosis
Internally funded
SPARC R B12 and carotid plaque
SPARC C Coenzyme Q10 for statin myopathy
SPARC C Cutaneous scarring and atherosclerosis
* HSFO is the Heart & Stroke Foundation of Ontario
* CIHR is the Canadian Institutes for Health Research
* NIH is the National Institutes of Health, USA
© 2008 Stroke Prevention & Atherosclerosis Research Centre (SPARC)

SPARC is Committed to Stroke Prevention