July 11, 2018 - From using CRISPR to alter the gut microbiome to looking at how the brain rewires itself in deafness, researchers at Schulich Medicine & Dentistry and Robarts Research Institute are the recipients of $11.3 million in project and bridge grant funding announced by the Canadian Institutes of Health Research (CIHR) this week.
There were a total of 17 funded projects across the School.
“This funding means everything to the success of our project,” said Dr. Walter Siqueira whose funded project is looking for novel ways to prevent and treat cavities using nanotechnology. “Being awarded this funding from CIHR is a big achievement for our group.”
These funds will aid researchers in continuing their work in exploring emerging questions in human health.
“The new grants from the Canadian Institutes of Health Research reflect the quality and the importance of the research that is being undertaken within our School,” said David Litchfield, Vice Dean of Research and Innovation at Schulich Medicine & Dentistry. “In addition to enabling new discoveries, this funding will promote advanced training for our next generation of scientists and health care professionals.”
Greta Bauer and Ayden Scheim
Co-applicants: Fin Gareau, Randy Jackson, Kelendria Nation, Renee Masching, Jake Pyne, Catherine G Taylor, Adrian E Edgar, Tatiana B Ferguson, Nathan J Lachowsky, Robb Travers, Jaimie Veale, Dominic Beaulieu‐Prévost, Todd Coleman, Yasmeen Persad, Nik Redman.
Trans PULSE Canada: A National Study of Transgender Health
Co-applicants: David H Birnie, Vladimir Hachinski, Jeff S Healey, Junmin Liu, Allan C Skanes, Luciano A Sposato.
Characterizing cerebral thrombus composition with Phase‐based MRI
David Edgell, Bogumil Karas, and Gregory Gloor
Co-applicants: David E Heinrichs.
ConCRISPR: Conjugative delivery of a hybrid CRISPR/Tev nuclease system for specific microbiota modulation in the mammalian gut
Co-applicants: Saverio Stranges, Bonnie Simpson, Sean Doherty, Jamie Seabrook, Leia Minaker, Piotr Wilk, Jess Haines, Colleen O'Connor, Kambiz Norozi,
Evaluation of a Smartphone Based Intervention for Improving Food Literacy, Food Purchasing, and Diet Quality Among Youth in Urban, Suburban, and Rural Environments
Co-applicants: Les Kalman, Mark Darling, Amin Rizkalla
Novel Biomaterials‐Based Strategies to Stimulate Periodontal Tissue Regeneration
Regulation of Salmonella pathogenesis by transposon‐encoded small regulatory RNAs
Effects of Neurodevelopmental Exposure to Cannabinoids on Prefrontal Cortical Function: Implications for Neuropsychiatric Disorders
Co-applicants: Blake Butler, Ravi Menon
Cortical Plasticity Following Deafness
Cholinergic influence in aging and brain pathology
Graham Reid and William Gardner
Co-applicants: Evelyn Vingilis, Kathleen Pajer, Jennifer Rayner, Jason Gilliland, Katholiki Georgiades, John Cairney, Judith Brown, Michael Boyle, Laura Duncan, Paul Kurdyak
Equity in Mental Health Care for Children and Youth
Co-applicants: Andrew Krahn
The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest: The EPS ARREST Study
Walter Siqueira and Elizabeth Gillies
Novel Drug Delivery System for the Combat of Dental Caries by using Salivary Peptides
Kathy Speechley and Karen Bax
Co-applicants: Mary Secco, Klajdi Puka, Simon Levin, Asuri Prasad, Guangyong Zou,
A Community-Based Family Treatment Program for Children with Epilepsy: A Randomized Controlled Trial
Co-applicants: Dean Betts, Basim Abu Rafea, Francis Tekpetey,
Understanding and Treating Obesity Related loss of Embryo Developmental Competence
Co-applicants: Robert Bartha, Murray Huff
Kir Channel Regulation by Membrane Lipids: An Enabler of Hemodynamic Sensing in the Cerebral Circulation
Projects funded through Lawson Health Research Institute:
Co-applicants: Rodrigo Bagur, Gerald Wisenberg, Shawn Whitehead, Nikolaos Tzemos, Marat Slessarev, Justin Hicks, Michael Kovacs, Ahmed Hegazy.
Selective Brain Hypothermia via Intranasal Cooling to Limit Brain Injury Post Cardiac Arrest
Co-applicants: Pierre Guy, David Wasserstein, Aileen Davis, Jeremy Hall, Jeffrey Hoch, Aaron Nauth, Brad Petrisor, Bill Ristevski, David Sanders, Gerard Slobogean, Wanrudee Isaranuwatchai, George Athwal, Abdel-Rahman Lawendy, Michael Mckee, Dorcas Beaton, Lauren Nowak, Patrick Henry, Gerald Lebovic, Mohit Bhandari.
The DECIPHER Study: DEterminants of Function and Clinically Important outcomes in Proximal Humerus Fractures in the Elder Population: A National CohoRt