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Our Publication List by Student (2002 to 2010)

The following list of publications is grouped by each student who has been enrolled in the CIHR Strategic Training Program in Vascular Research.
Peer-reviewed Publications:

Salam Al-Attar
Al-Attar SA, Pollex RL, Ban MR, Young TK, Bjerregaard P, Anand SS, Yusuf S, Zinman B, Harris SB, Hanley AJG, Connelly PW, Huff MW, Hegele RA. Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a multi-ethnic sample. Cardiovasc Diabetol. 2008 Mar 13;7:5.

Hegele RA, Al-Attar SA, Rutt BK. Obstructive sleep apnea in two women with familial partial lipodystrophy due to a heterozygous LMNA R482Q mutation. CMAJ (2007), 177(7):743-5.

Hegele RA, Joy TR, Al-Attar SA, Rutt BF. Thematic review series: Adipocyte Biology. Lipodystrophies: windows on adipose biology and metabolism. J Lipid Res. (2007), 48(7):1433-44. (PMID: 17374881)

Al-Attar SA, Pollex RL, Robinson JF, Miskie BE, Walcarius R, Harper Little C, Rutt BF, Hegele RA. Quantitative and qualitative differences in subcutaneous adipose tissue stores across lipodystrophy types shown by magnetic resonance imaging. BMC Med Imaging (2007), 7(1):3.

Al-Attar SA, Pollex RL, Robinson JF, Miskie BE, Walcarius R, Rutt BF, Hegele RA. Semi-automated  segmentation and quantification of adipose tissue in calf and thigh by MRI: a preliminary study in patients with monogenic metabolic syndrome. BMC Med Imaging (2006), 6(1):11.

Khalid Al-Shali
Yuan G, Al-Shali KZ, Hegele RA. Hypertriglyceridemia: its etiology, effects and treatment. CMAJ. 2007 Apr 10;176(8):1113-20. Review.

Pollex RL, Al-Shali KZ, House AA, Spence JD, Fenster A, Mamakeesick M, Zinman B, Harris SB, Hanley AJ, Hegele RA. Relationship of the metabolic syndrome to carotid ultrasound traits. Cardiovasc Ultrasound. 2006 Jul 7;4:28.

Hegele RA, Al-Shali KZ, House AA, Hanley AJ, Harris SB, Mamakeesick M, Fenster A, Zinman B, Cao H, Spence JD. Disparate associations of a functional promoter polymorphism in PCK1 with carotid wall ultrasound traits. Stroke. 2005 Dec;36(12):2566-70. Epub 2005 Nov 10.

Al-Shali K, House AA, Hanley AJ, Khan HM, Harris SB, Mamakeesick M, Zinman B, Fenster A, Spence JD, Hegele RA. Differences between carotid wall morphological phenotypes measured by ultrasound in one, two and three dimensions. Atherosclerosis. 2005 Feb;178(2):319-25.

Al-Shali KZ, House AA, Hanley AJ, Khan HM, Harris SB, Zinman B, Mamakeesick M, Fenster A, Spence JD, Hegele RA. Genetic variation in PPARG encoding peroxisome proliferator-activated receptor gamma associated with carotid atherosclerosis. Stroke. 2004 35(9):2036-40.

Al-Shali K, and Hegele R. Laminopathies and atherosclerosis. Arterioscler Thromb Vasc Biol. 2004 24(9):1591-5.

Al-Shali K, Wang J, Rosen F, Hegele RA. Ileal adenocarcinoma in a mild phenotype of abetalipoproteinemia. Clin Genet. 2003 Feb;63(2):135-8.

Al-Shali K, Cao H, Knoers N, Hermus AR, Tack CJ, Hegele R. A single base mutation in the peroxisome proliferator-activated receptor gamma4 promoter associated with altered in vitro expression and partial lipodystrophy. Journal of Clinical Endocrinology and Metabolism Nov 2004 89(11):5655-60).

Al-Shali K, House A, Hanley A, Khan H, Harris S, Mamakeesick M, Zinman B, Fenster A, Spence JD, Hegele R. Differences between carotid wall morphological phenotypes measures by ultrasound in one, two and three dimensions. Atherosclerosis 2005 Feb;178(2):319-25

Zareen Amtul
Amtul, Z., M. Uhrig, and K. Beyreuther. 2011. Additive effects of fatty acid mixtures on the levels and ratio of amyloid beta40/42 peptides differ from the effects of individual fatty acids. Journal of Neuroscience Research (Jul 11).

Amtul, Z., M. Uhrig, R. F. Rozmahel, and K. Beyreuther. 2011. Structural insight into the differential effects of omega-3 and omega-6 fatty acids on the production of abeta peptides and amyloid plaques. The Journal of Biological Chemistry 286 (8) (Feb 25): 6100-7.

Amtul, Z., M. Uhrig, R. Supino, and K. Beyreuther. 2010. Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios. Neuroscience Letters 481 (2) (Sep 6): 73-7.

Amtul, Z., L. Wang, D. Westaway, and R. F. Rozmahel. 2010. Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease. Neuroscience 169 (2) (Aug 25): 781-6.

Amtul, Z., D. Westaway, D. F. Cechetto, and R. F. Rozmahel. 2011. Oleic acid ameliorates amyloidosis in cellular and mouse models of Alzheimer's disease. Brain Pathology (Zurich, Switzerland) 21 (3) (May): 321-9.

Julia Assini
Mulvihill, E. E., J. M. Assini, J. K. Lee, E. M. Allister, B. G. Sutherland, J. B. Koppes, C. G. Sawyez, et al. 2011. Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance. Diabetes 60 (5) (May): 1446-57.

Mulvihill, E. E., J. M. Assini, B. G. Sutherland, A. S. DiMattia, M. Khami, J. B. Koppes, C. G. Sawyez, S. C. Whitman, and M. W. Huff. 2010. Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice. Arteriosclerosis, Thrombosis, and Vascular Biology 30 (4) (Apr): 742-8.

Joseph Awad
Awad J, Krasinski A, Parraga G, Fenster A. Texture analysis of carotid artery atherosclerosis from three-dimensional ultrasound images. Med Phys. 2010 Apr;37(4):1382-91.

Fereshteh Bahramian
Bahramian F., Straatman A. G., "A volume-based discrete test filter for conducting Large Eddy Simulations with application to physiological flow in a constricted tube", International Journal for Numerical Methods in Fluids, 2009.

Michael Beyea
Michael M. Beyea, Claire L. Heslop, Cynthia G. Sawyez, Jane Y. Edwards, Janet G. Markle, Robert A. Hegele, and Murray W. Huff. Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol. Feb 23 2007;282(8):5207-16. Epub 2006 Dec 23.

Kimberley Blackwood
Blackwood KJ, Lewden B, Wells RG, Sykes J, Stodilka RZ, Wisenberg G, Prato FS. In vivo SPECT quantification of transplanted cell survival following engraftment using 111In-tropolone in infarcted canine myocardium. Journal of Nuclear Medicine June 2009;50:927-935.

Blackwood KJ, Stodilka RZ, Prato FS. Imaging regenerative therapy with hybrid technology: restoring broken hearts. Interactions. 2006;52(4): 141-155.

Stodilka RZ, Blackwood KJ, Prato FS. Tracking transplanted cells using dual-radionuclide SPECT. Physics in Medicine & Biology. 2006; 51:2619-2632;

Stodilka RZ, Blackwood KJ, Kong H, Prato FS. A method for quantitative cell tracking using SPECT for the evaluation of myocardial stem cell therapy. Nuc Med Commun. 2006; 27:807-813.

Bernard Chiu (also with ND Nanayakkara and M Egger)
B. Chiu, A. Krasinski, J.D. Spence, G. Parraga and A. Fenster, “Three-dimensional carotid ultrasound segmentation variability dependence on signal difference and boundary orientation.” Ultrasound Med Biol. 2010 Jan;36(1):95-110.

B. Chiu, V. Beletsky, J.D. Spence, G. Parraga and A. Fenster, “Analysis of carotid lumen surface morphology using 3-dimensional ultrasound imaging,” Physics in Medicine and Biology, Vol. 54, No.5, pp. 1149-1167, 2009.

N.D. Nanayakkara, B. Chiu, A. Samani, J.D. Spence, J. Samarabandu, G. Parraga and A. Fenster, “Nonrigid registration of three-dimensional ultrasound and magnetic resonance images of the carotid arteries,” Med. Phys. Vol. 36, No. 2, pp. 373-385, 2009.

Chiu B, Egger M, Spence JD, Parraga G, Fenster A. Quantification of carotid vessel wall and plaque thickness change using 3D ultrasound images. Med Phys. 2008 Aug;35(8):3691-710.

Chiu B, Egger M, Spence DJ, Parraga G, Fenster A. Comparison of B-mode ultrasound, 3-dimensional ultrasound, and magnetic resonance imaging measurements of carotid atherosclerosis. Med Phys. 2008 Aug;35(8):3691-710.

Egger M, Chiu B, Spence JD, Fenster A, Parraga G. Mapping spatial and temporal changes in carotid atherosclerosis from three-dimensional ultrasound images. Ultrasound Med Biol. 2008 Jan;34(1):64-72. Epub 2007 Aug 27.

Chiu B, Egger M, Spence DJ, Parraga G, Fenster A. Area-preserving flattening maps of 3D ultrasound carotid arteries images. Med Image Anal. 2008 May 7. [Epub ahead of print]

Ding M, Chiu B, Gyacskov I, Yuan X, Drangova M, Downey DB, Fenster A. Fast prostate segmentation in 3D TRUS images based on continuity constraint using an autoregressive model. Med Phys. 2007 Nov;34(11):4109-25.

Chiu B, Egger M, Spence JD, Parraga G, Fenster A. Quantification of progression and regression of carotid vessel atherosclerosis using 3D ultrasound images. Conf Proc IEEE Eng Med Biol Soc. 2006;1:3819-22.

Nanayakkara ND, Chiu B, Samani A, Spence JD, Samarabandu J, Fenster A. A non-rigid image registration technique for 3D ultrasound carotid images using a "twisting and bending" model. Conf Proc IEEE Eng Med Biol Soc. 2006;1:2738-41.

W. Y. Song, B. Chiu and G. S. Bauman et al., Prostate contouring uncertainty in megavoltage computed tomography images acquired with a helical tomotherapy unit during image-guided radiation therapy, Int. J. Radiat. Oncol. Biol. Phys., vol. 65, pp. 595-607, Jun 1. 2006.

Chiu, B., Freeman, G.H., Salama, M.M.A. and Fenster, A. Prostate segmentation algorithm using dyadic wavelet transform and discrete dynamic contour. Physics in Medicine and Biology. 2004 49(21): 4943-4960.

Daniel Cho
Linte CA, Lang P, Rettmann ME, Cho DS, Holmes III DR, Robb RA and Peters TM. Accuracy considerations in image-guided cardiac interventions: Experience and lessons learned. Int J CARS. DOI: 10.1007/s11548-011-0621-1. Jun 2011 (in Press).

Sarah Detombe
Graham KC, Detombe SA, MacKenzie LT, Holdsworth DW, MacDonald IC, Chambers AF, Drangova M. Contrast-enhanced microcomputed tomography using intraperitoneal contrast injection for the assessment of tumor-burden in liver metastasis models. Invest Radiol. 2008 Jul;43(7):488-95.

Detombe SA, Ford NL, Xiang F, Lu X, Feng Q, Drangova M. Longitudinal follow-up of cardiac structure and functional changes in an infarct mouse model using retrospectively gated micro-computed tomography. Invest Radiol. 2008 Jul;43(7):520-9. 24.

Drangova M, Ford NL, Detombe SA, Wheatley AR, Holdsworth DW. (2006) Fast retrospectively gated quantitative 4D cardiac micro-CT imaging of free-breathing mice. Invest Radiol. 42(2): 85-94. (50%)

Graham KC, Detombe SA, MacKenzie LT, et al. Contrast-enhanced microcomputed tomography using intraperitoneal contrast injection for the assessment of tumor-burden in liver metastasis models. Invest Radiol 2008 Jul; 43(7):488-95.

Detombe SA, Ford NL, Xiang FL, Lu X, Feng Q, Drangova M. Evaluating Cardiac Structure and Function in an Infarct Mouse Model using Retrospectively Gated Micro-CT. submitted to Circulation August 2007.

Sudipto Dolui
Michailovich, O., Y. Rathi, and S. Dolui. 2011. Spatially regularized compressed sensing for high angular resolution diffusion imaging. IEEE Transactions on Medical Imaging 30 (5) (May): 1100-15.

Joseph Dube
Dube, J. B., C. T. Johansen, and R. A. Hegele. 2011. Sortilin: An unusual suspect in cholesterol metabolism: From GWAS identification to in vivo biochemical analyses, sortilin has been identified as a novel mediator of human lipoprotein metabolism. BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology 33 (6) (Jun): 430-7.

Micaela Egger
Egger M, Krasinski A, Rutt BK, Fenster A, Parraga G. Comparison of B-mode ultrasound, 3-dimensional ultrasound, and magnetic resonance imaging measurements of carotid atherosclerosis. J Ultrasound Med. 2008 Sep;27(9):1321-34.

Egger M, Chiu B, Spence JD, Fenster A, Parraga G. Mapping spatial and temporal changes in carotid atherosclerosis from 3-dimensional ultrasound images. Ultrasound Med Biol. 2007 Aug 24; [Epub ahead of print].

Egger M, Spence JD, Fenster A, Parraga G. Validation of 3D ultrasound vessel wall volume: an imaging phenotype of carotid atherosclerosis. Ultrasound Med Biol. 2007 Jun;33(6):905-14. Epub 2007 Apr 18.

Chiu B, Egger M, Spence JD, Parraga G, Fenster A. Quantification of progression and regression of carotid vessel atherosclerosis using 3D ultrasound images. Conf Proc IEEE Eng Med Biol Soc. 2006;1:3819-22.

Matthew Ford
Ford MD, Xie YJ, Wasserman BA, Steinman DA. Is flow in the common carotid artery fully developed? Physiol Meas. 2008 Nov;29(11):1335-49. Epub 2008 Oct 14.

Ford MD, Hoi Y, Piccinelli M, Antiga L, Steinman DA. An objective approach to digital removal of saccular aneurysms: technique and applications. Br J Radiol. 2009 Jan;82 Spec No 1:S55-61.

Ford MD, Lee SW, Lownie SP, Holdsworth DW, Steinman DA. On the effect of parent-aneurysm angle on flow patterns in basilar tip aneurysms: towards a surrogate geometric marker of intra-aneurismal hemodynamics. J Biomech. 2008;41(2):241-8.

Ford MD; Nikolov H.; Milner J; Lownie SP; DeMont EM; Kalata W; Loth F; Holdsworth DW; Steinman DA. PIV-measured versus CFD-predicted flow dynamics in anatomically realistic cerebral aneurysm models. Journal of Biomechanical Engineering, v 130, n 2, April, 2008, p 021015

Ford, M.D., Stuhne G.R., Nikolov H.N., Habets, D.F., Lownie S.P., Holdsworth D.W., Steinman D.A.(2005). Virtual Angiography for Visualization and Validation of Computational Fluid Dynamics Models of Aneurysm Hemodynamics. IEEE Transactions in Medical Imaging, 2005 Dec;24(12):1586-92.

Ford, M.D., Alperin, N, Lee, S.H., Holdsworth, D.W., and Steinman, D.A. Characterization of Volumetric Flow Rate Waveforms in the Normal Carotid and Vertebral Arteries. Physiological Measurement. 2005 Vol. 26: 477-488.

Christina Godin
Godin CM, Ferguson SS. The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase. Mol Pharmacol. 2010 Jun;77(6):903-11. Epub 2010 Feb 24.

Godin CM, Ferreira LT, Dale LB, Gros R, Cregan SP, Ferguson SS. The small GTPase Ral couples the angiotensin II type 1 receptor to the activation of phospholipase C-delta 1. Mol Pharmacol. 2010 Mar;77(3):388-95. Epub 2009 Dec 16.

ADVANCE Collaborative Group, Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, Marre M, Cooper M, Glasziou P, Grobbee D, Hamet P, Harrap S, Heller S, Liu L, Mancia G, Mogensen CE, Pan C, Poulter N, Rodgers A, Williams B, Bompoint S, de Galan BE, Joshi R, Travert F. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008 Jun 12;358(24):2560-72. Epub 2008 Jun 6.

Anborgh PH, Godin C, Pampillo M, Dhami GK, Dale LB, Cregan SP, Truant R, Ferguson SS. Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. J Biol Chem. 2005 Oct 14;280(41):34840-8. Epub 2005 Aug 9.

Bhattacharya M, Babwah AV, Godin C, Anborgh PH, Dale LB, Poulter MO, Ferguson SS. Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis. Journal of Neuroscience. 2004 Oct 6;24(40):8752-61.

Derek Hyde
Hyde DE, Habets DF, Fox AJ, Gulka I, Kalapos P, Lee DH, Pelz DM, Holdsworth DW. Comparison of maximum intensity projection and digitally reconstructed radiographic projection for carotid artery stenosis measurement. Medical Physics. 2007 Jul;34(7):2968-74.

Hyde DE, Fox AJ, Gulka I, Kalapos P, Lee DH, Pelz DM, Holdsworth DW. Internal carotid artery stenosis measurement: comparison of 3D computed rotational angiography and conventional digital subtraction angiography. Stroke 2004 Dec;35(12):2776-81. Epub 2004 Oct 28.

Christopher Johansen
ohansen CT, Wang J, Lanktree MB, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Cao H, Hegele RA. An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1916-26. Epub 2011 May 19.

Johansen CT, Lanktree MB, Hegele RA. Translating genomic analyses into improved management of coronary artery disease. Future Cardiol. 2010 Jul;6(4):507-21. Review. PubMed PMID: 20608823.

Johansen CT, Wang J, Lanktree MB, Cao H, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Hegele RA. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet. 2010 Aug;42(8):684-7. Epub 2010 Jul 25. PubMed PMID: 20657596; PubMed Central PMCID: PMC3017369.

Johansen, C.T. and Hegele, R.A. (2009) Predictive genetic testing for coronary artery disease. Critical Reviews in Clinical Laboratory Sciences. 2009;46(5-6):343-60. Review.

Karas, B., Amyot, L., Johansen, C., Sato, S., Tabata, Y., Kawaguchi, M., and Szczyglowski, K. (2009) Functional conservation of Lotus japonicus and Arabidopsis basic helix-loop-helix proteins reveal new players in root hair development. Plant Physiology. 2009 Nov;151(3):1175-85. Epub 2009 Aug 12.

Johansen, C.T., Gallinger, Z., Young, T.K., Wang, J., Ban, M.R., Bjerregaard, P., and Hegele, R.A. (2009) Rare ATGL haplotypes are associated with increased plasma triglycerides in the Greenland Inuit. International Journal of Circumpolar Health 2010 Feb;69(1):3-12.

Karen Kennedy
Kennedy KA, Ostrakhovitch EA, Sandiford SD, Dayarathna T, Xie X, Waese EY, Chang WY, Feng Q, Skerjanc IS, Stanford WL, Li SS. Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells. J Biol Chem. 2010 Jun 4;285(23):17974-85. Epub 2010 Mar 16.

Karen A. M. Kennedy, Tammy Porter, Virja Mehta, Scott D. Ryan , Feodor Price, Vian Peshdary, Christina Karamboulas, Josée Savage, Thomas A. Drysdale|, Shun-Cheng Li, Steffany A.L. Bennett, and Ilona S. Skerjanc. (2009) Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by Bone Morphogenetic Protein 4 but not dominant negative ß-catenin. BMC Biology 2009, 7:67

Zamir Khan
Khan Z, Boughner DR, Lacefield JC. Anisotropy of high-frequency integrated backscatter from aortic valve cusps. Ultrasound Med Biol. 2008 Sep;34(9):1504-12. Epub 2008 Apr 14

Mahdieh Khoshniat
Khoshniat M, Thorne ML, Poepping TL, Hirji S, Holdsworth DW, Steinman DA. Real-time numerical simulation of Doppler ultrasound in the presence of nonaxial flow. Ultrasound in Medicine and Biology. 2005 Apr;31(4):519-28.

Miranda Kirby (MSc)
Kirby M, Svenningsen S, Ahmed H, Wheatley A, Etemad-Rezai R, Paterson NA, Parraga G. Quantitative evaluation of hyperpolarized helium-3 magnetic resonance imaging of lung function variability in cystic fibrosis. Acad Radiol. 2011 Aug;18(8):1006-13. Epub 2011 May 4.

M Kirby, L Mathew, A Wheatley, DG McCormack and G Parraga. Chronic Obstructive Pulmonary Disease Progression Detected by Hyperpolarized Helium-3 Magnetic Resonance Imaging. Radiology. 2010 Jul;256(1):280-9.

L Mathew, M Kirby, R Etemad-Rezai, A Wheatley, DG McCormack and G Parraga. Hyperpolarized 3He Magnetic Resonance Imaging: Preliminary Evaluation of Phenotyping Potential in Chronic Obstructive Pulmonary Disease. Eur J Radiol. 2009 Nov 20

Renee Korol
Lucas, A. R., Korol, R., Pepine, C. J. Inflammation in atherosclerosis: some thoughts about acute coronary syndromes. Circulation 2006 May 2;113(17):e728-32. Review.

Korol, R. M., Canham, P. B., and A.R. Lucas. Multiple Regression Analysis. Biophotonics International. August 2005: 47-48.

Christov, A., Korol, R.M., Dai, E., Liu, L., Guan, H., Bernards, M., Cavers, P., Susko, D., Lucas, A.R. In vivo optical analysis of quantitative changes in collagen and elastin during arterial remodeling. Photochem & Photobio 2005 Vol. 81, pp.457-66 7.

R. Korol, H. Finlay, M. Josseau, A. Lucas, P. Canham. Fluorescence spectroscopy and birefringence measurements of molecular changes in maturing rat tail tendon. J Biomed Opt. 2007 Mar-Apr; 12(2):024011.

A. Christov, R. Korol, E. Dai, L. Liu, H. Guan, M. Bernards, P. Cavers, D. Susko, A. Lucas. In vivo optical analysis of quantitative changes in collagen and elastin during arterial remodeling. Photchem & Photobio; Mar 1, 2004 [Epub ahead of print]. Photochem Photobiol. 2005 Mar-Apr;81(2):457-66.

R. Korol, B. Bikersteth, V. Yang, S. Dimov, P. Vatsya, M. Gordon, A. Vitkin, L. Liu, P. Canham, S. Clarke, A. Lucas. Semi-Quantitative Analysis of Atherosclerotic Plaque using Optical Coherence Tomography and Time-of-Flight Secondary Ion Mass Spectrometry. Optical Coherence Tomography and Coherence Techniques, Proceedings of SPIE Vol. 5140: 212-220, 2003.

Adam Krasinsky
Awad J, Krasinski A, Parraga G, Fenster A. Texture analysis of carotid artery atherosclerosis from three-dimensional ultrasound images. Med Phys. 2010 Apr;37(4):1382-91.

A. Krasinski, B. Chiu, J.D. Spence, A. Fenster and G. Parraga, “Three-dimensional ultrasound quantification of intensive statin treatment of carotid atherosclerosis.” Ultrasound Med Biol. 2009 Nov;35(11):1763-72. Epub 2009 Aug 3.

A. Krasinski, B Chiu, A Fenster, G Parraga. Magnetic Resonance Imaging and Three-dimensional Ultrasound of Carotid Atherosclerosis: Mapping Regional Differences. Submitted: J Magn Reson Imaging July 2008.

Piya Lahiry
Lahiry P, Torkamani A, Schork NJ, Hegele RA. Kinase mutations in human disease: interpreting genotype-phenotype relationships. Nat Rev Genet. 2010 Jan;11(1):60-74. Review.

Lahiry P, Cao H, Ban MR, Pollex RL, Mamakeesick M, Zinman B, Harris SB, Hanley AJ, Huff MW, Connelly PW, Hegele RA. APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians. Am J Hum Genet. 2009 Feb;84(2):134-47. Epub 2009 Jan 29.

Lahiry P, Wang J, Robinson JF, Turowec JP, Litchfield DW, Lanktree MB, Gloor GB, Puffenberger EG, Strauss KA, Martens MB, Ramsay DA, Rupar CA, Siu V, Hegele RA. A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems. Am J Hum Genet. 2009 Feb;84(2):134-47. Epub 2009 Jan 29. Erratum in: Am J Hum Genet. 2009 Jun;84(6):822. (1)

Joy T, Lahiry P, Pollex RL, Hegele RA. Genetics of metabolic syndrome: is there a role for phenomics? Curr Atheroscler Rep. 2008 Jun;10(3):201-8. Review. (6)

Piya Lahiry, Rebecca L. Pollex, Robert A. Hegele. Uncloaking the Genetic Determinants of Metabolic Syndrome. J Nutrigenet Nutrigenomics 2008;1:118-125 (2)

Lahiry P, Ban MR, Pollex RL, Feldman RD, Sawyez CG, Huff MW, Young TK, Bjerregaard P, Hegele RA. Common variants APOC3, APOA5, APOE and PON1 are associated with variation in plasma lipoprotein traits in Greenlanders. Int J Circumpolar Health. 2007 Dec;66(5):390-400. (2)

Matthew Lanktree
Lanktree MB, Guo Y, Murtaza M, et al. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet. 2011 Jan 7;88(1):6-18. Epub 2010 Dec 30. PubMed PMID: 21194676; PubMed Central PMCID: PMC3014369

Li Y, Laue K, Temtamy S, Aglan M, Kotan LD, Yigit G, Canan H, Pawlik B, Nürnberg G, Wakeling EL, Quarrell OW, Baessmann I, Lanktree MB, Yilmaz M, Hegele RA, et al. Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations inchondroitin synthase 1, a potential target of BMP signaling. Am J Hum Genet. 2010 Dec 10;87(6):757-67. PubMed PMID: 21129728; PubMed Central PMCID: PMC2997369.

Lanktree MB, Johansen CT, Anand SS, Davis AD, Miller R, Yusuf S, Hegele RA. Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration. Blood. 2010 Jun 17. [Epub ahead of print]

Lanktree MB, Hegele RA, Schork NJ, Spence JD. Extremes of unexplained variation as a phenotype: an efficient approach for genome-wide association studies of cardiovascular disease. Circ Cardiovasc Genet. 2010 Apr;3(2):215-21.

Lanktree MB, Hassell RG, Lahiry P, Hegele RA. Phenomics: expanding the role of clinical evaluation in genomic studies. J Investig Med. 2010 Jun;58(5):700-6.

Lanktree MB, Dichgans M, Hegele RA. Advances in genomic analysis of stroke: what have we learned and where are we headed? Stroke. 2010 Apr;41(4):825-32. Epub 2010 Feb 18. Review.

Lanktree MB, Anand SS, Yusuf S, Hegele RA; SHARE Investigators. Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese, and European Caucasians. Circ Cardiovasc Genet. 2010 Feb 1;3(1):39-46. Epub 2009 Dec 30.

Lanktree MB, Fantus IG, Hegele RA. Triple X syndrome in a patient with partial lipodystrophy discovered using a high-density oligonucleotide microarray: a case report. J Med Case Reports. 2009 Aug 12;3:8867.

Lanktree MB, Hegele RA, Yusuf S, Anand SS, and the SHARE investigators (2009) Multi-ethnic genetic association study of carotid intima-media thickness using a targeted cardiovascular SNP microarray. Stroke 40:10:3173-9.

Lanktree MB, Anand SS, Yusuf S, Hegele RA, and the SHARE investigators (2009) Replication of genetic associations with plasma lipoproteins and triglycerides in a multi- ethnic sample using a targeted cardiovascular SNP microarray. J Lipid Res 50:7:1487-96.

Lanktree MB, Fantus IG, Hegele RA (2009) Triple X syndrome in a patient with partial lipodystrophy discovered with high-density oligonucleotide microarray: a case report. J Medical Case Reports 12:3:8867.

Lanktree MB, Hegele RA (2009) Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease. Genome Med 1:2:28.

Lanktree MB, Rajakumar C, Brunt JH, Koschinsky ML, Connelly PW, Hegele RA (2009) Determination of lipoprotein(a) kringle repeat number from genomic DNA: Copy number variation genotyping using quantitative real-time PCR. J Lipid Res 50:4:768-72.

Lanktree M, Hegele RA (2008) Copy number variation in metabolic phenotypes. Genomic Cytogenetic Res 123:1-4:169-175.

Lanktree M, Squassina A, Krinsky M, Strauss J, Jain U, Macciardi F, Kennedy JL, Muglia P (2008) Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. Am J Med Genet 147B:6:945-51.

Lanktree M, Hegele RA, Yusuf S, and Anand SS. Multi-Ethnic Genetic Association Study of Carotid Intima-Media Thickness Using a Targeted Cardiovascular SNP Microarray. Online Stroke: Published online before print August 13, 2009, doi: 10.1161/ STROKEAHA.109.556563

Lanktree M, Cao H, Rabkin SW, Hanna A, Hegele RA. Novel LMNA mutations seen in patients with familial partial lipodystrophy subtype 2 (FPLD2; MIM 151660). Clin Genet. 2007 Feb;71(2):183-6.

Amanda Laslo
Laslo AM, Eastwood JD, Pakkiri P, Chen F, Lee TY. CT perfusion-derived mean transit time predicts early mortality and delayed vasospasm after experimental subarachnoid hemorrhage. AJNR Am J Neuroradiol. 2008 Jan;29(1):79-85. Epub 2007 Oct 26.

Laslo AM, Eastwood JD, Chen FX, Lee TY. Dynamic CT perfusion imaging in subarachnoid hemorrhage-related vasospasm. AJNR Am J Neuroradiol. 2006 Mar;27(3):624-31.

Laslo AM, Eastwood JD, Urquhart B, Lee TY, Freeman D. Subcutaneous nimodipine improves bioavailability in rabbits. Journal of Neuroscience Methods. 2004, 139(2): 195-201.

Cristian Linte
Linte C, Moore J, Wedlake C, Peters T. Evaluation of Model-Enhanced Ultrasound-Assisted Interventional Guidance in a Cardiac Phantom. IEEE Trans Biomed Eng. 2010 May 27. [Epub ahead of print].

Linte CA, Moore, J, Wedlake C, Bainbridge D, Guiraudon GM, Jones DL and Peters TM. Inside the Beating Heart: An In Vivo Feasibility Study on Fusing Pre- and Intra-operative Imaging for Minimally Invasive Therapy. Journal of Computer Assisted Radiology and Surgery. Vol. 4(2). Pp. 113-23. 2009.

Linte CA. Medicine through the eyes of an engineer: strengthening the engineer--physician collaborations. IEEE Eng Med Biol Mag. 2009 Sep-Oct;28(5):8-10, 65.

Linte CA. The nuts and bolts of EMBS student chapters! IEEE Eng Med Biol Mag. 2009 Mar-Apr;28(2):8-10.

Linte CA, Wierzbicki M, Peters TM, Samani A. Towards a biomechanics-based technique for assessing myocardial contractility: an inverse problem approach. Comput Methods Biomech Biomed Engin. 2008 Jun;11(3):243-55.

Linte CA, Moore J, Wiles AD, Wedlake C, Peters TM. Virtual reality-enhanced ultrasound guidance: a novel technique for intracardiac interventions. Comput Aided Surg. 2008 Mar;13(2):82-94.

Linte CA. Writing for publication in biomedical engineering. IEEE Eng Med Biol Mag. 2008 May-Jun;27(3):7-11.

Linte CA. Student's corner. Undergraduate student successfully invents artificial Golgi. IEEE Eng Med Biol Mag. 2008 Sep-Oct;27(5):9-10.

Linte C. Student's Corner. IEEE Eng Med Biol Mag. 2008 Sep-Jan0;27(5):9-10.

Michael Lizardo
Lizardo MM, Macdonald IC, Tuck AB, Chambers AE. A new breast cancer model for lymphatic metastasis. Cancer Treat Res. 2007;135:157-65.

Suanne Mahabir
Mahabir S, Wan W, Katsaras J, Nieh MP Effects of charge density and thermal history on the morphologies of spontaneously formed unilamellar vesicles. J Phys Chem B. 2010 May 6;114(17):5729-35.

Christiane Mallett
I. Shai, J. D. Spence, D. Schwarzfuchs, Y. Henkin, G. Paragga, A. Rudich, A. Fenster, C. Mallett, N. Liel, A. Tirosh, A. Bolotin, J. Thiery, G.M. Fiedler, M. Blüher, M. Stumvoll, M.J. Stampfer for the DIRECT group. Dietary Intervention to Reverse Carotid Atherosclerosis. Circulation. 2010 Mar 16;121(10):1200-8. Epub 2010 Mar 1.

C L. Mallett, L. Gardi, A. Fenster, G. Parraga. Prospective Cardiac Gating of Carotid Three-Dimensional Ultrasound. Medical Physics 2009 36(7): 3168-3175.

C. L. Mallett, A. A. House, J.D. Spence, A. Fenster, G. Parraga. Longitudinal measurement of carotid atherosclerosis in one, two and three dimensions. Ultrasound in Medicine and Biology 2009 35(3):367-75.

C. Mallett, L. Gardi, J. Pope, J.D. Spence, A. Fenster, G. Parraga. Development of cardiac-gated 3-dimensional ultrasound imaging of carotid atherosclerosis. Medical Physics 2007 34(6): 2332

Phil Medeiros
Medeiros PJ, Al-Khazraji BK, Novielli NM, Postovit LM, Chambers AF, Jackson DN. Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line. Int J Cancer. 2011 Aug 5. Doi: 10.1002/ijc.26350. [Epub ahead of print]

Leonardo Millon
Millon LE, Guhados G, Wan W. Anisotropic polyvinyl alcohol-Bacterial cellulose nanocomposite for biomedical applications. J Biomed Mater Res B Appl Biomater. 2008 Feb 20; [Epub ahead of print]

Millon LE, Nieh M-P, Hutter JL, WK Wan. SANS characterization of an anisotropic poly(vinyl alcohol) hydrogel with vascular applications. Macromolecules, v 40, n 10, May 15, 2007, p 3655-3662.

Millon, LE, WK Wan. The polyvinyl alcohol-bacterial cellulose system as a new nanocomposite for biomedical applications. J Biomedical Materials Research Part B Applied Biomaterials. 2006;79(2):245-53.

Millon LE, Mohammadi, H. and Wan WK. Anisotropic polyvinyl alcohol hydrogel for cardiovascular applications. J Biomedical Materials Research Part B Applied Biomaterials. 2006;79(2):305-11.

Andrea Mitchell
Mitchell AJ, Sabondjian E, Sykes J, Deans L, Zhu W, Lu X, Feng Q, Prato FS, Wisenberg G. Comparison of initial cell retention and clearance kinetics after subendocardial or subepicardial injections of endothelial progenitor cells in a canine myocardial infarction model. J Nucl Med. 2010 Mar;51(3):413-7. Epub 2010 Feb 11.

Mohammadi, H.
Millon LE, Mohammadi H, Wan WK. Anisotropic polyvinyl alcohol hydrogel for cardiovascular applications. J Biomed Mater Res B Appl Biomater. 2006 Nov;79(2):305-11.

Mohammadi, H. Ahmadian MT, Wan WK. Time-dependent analysis of leaflets in mechanical aortic bileaflet heart valves in closing phase using the finite strip method. Medical Engineering and Physics, v 28, n 2, March, 2006, p 122-133

Erin Mulvihill
Allister EM, Mulvihill EE, Barrett PH, Edwards JY, Carter LP, Huff MW. Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor. J Lipid Res. 2008 Oct;49(10):2218-29. Epub 2008 Jun 27.

Bowley E, Mulvihill E, Howard JC, Pak BJ, Gan BS, O’Gorman DB. A novel mass spectrometry-based assay for GSK-3beta activity. BMC Biochemistry 2005 Dec 16;6:29

Blake Murphy
Lee TY, Murphy BD, Aviv RI, Fox AJ, Black SE, Sahlas DJ, Symons S, Lee DH, Pelz D, Gulka IB, Chan R, Beletsky V, Hachinski V, Hogan MJ, Goyal M, Demchuk AM, Coutts SB. Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke: a systematic review. Stroke. 2006 Sep;37(9):2201; author reply 2203. Epub 2006 Aug 3.

Murphy BD, Fox AJ, Lee DH, Sahlas DJ, Black SE, Hogan MJ, Coutts SB, Demchuk AM, Goyal M, Aviv RI, Symons S, Gulka IB, Beletsky V, Pelz D, Hachinski V, Chan R, Lee TY. Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements. Stroke. 2006 Jul;37(7):1771-7. Epub 2006 Jun 8.

Murphy BD, Chen X, Lee TY Serial Changes in CT Cerebral Blood Volume and Flow after Four Hours of Middle Cerebral Occlusion in an Animal Model of Embolic Cerebral Ischemia. AJNR – American Journal of Neuroradiology 2007 Apr;28(4):743-9.

Murphy B, Krieger C, Hoffer JA. Chronically implanted epineurial electrodes for repeated assessment of nerve conduction velocity and compound action potential in rodents, Journal of Neuroscience Methods, 2004 132(1):25-33

Mohammad Nambakhsh
Nambakhsh MS, Yuan J, Ben Ayed I, Punithakumar K, Goela A, Islam A, Peters T, Li S. A convex max-flow segmentation of LV using subject-specific distributions on cardiac MRI. Inf Process Med Imaging. 2011;22:171-83

Nuwan Nanayakkara
Nanayakkara ND; Chiu B; Samani A; Spence J.D; Parraga G; Samarabandu J; Fenster, A. Nonrigid registration of carotid ultrasound and MR images using a "twisting and bending" model. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v 6914, Medical Imaging 2008: Image Processing, 2008, p 691411

Nanayakkara ND, Chiu B, Samani A, Spence JD, Samarabandu J, Fenster A. A non-rigid image registration technique for 3D ultrasound carotid images using a "twisting and bending" model. Conf Proc IEEE Eng Med Biol Soc. 2006;1:2738-41.

Nanayakkara ND, Samarabandu J, Fenster A. Prostate segmentation by feature enhancement using domain knowledge and adaptive region based operations. Physics in Medicine and Biology vol. 51(7) April 2006, pp. 1831-1848

N. D. Nanayakkara, B. Chiu, A. Samani, D. Spence, J. Samarabandu, and A. Fenster. A `Twisting and Bending' Model based Nonrigid Image Registration Technique for 3D Ultrasound Carotid Images," in IEEE Transactions on Medical Imaging, resubmitted after revisions on Sep. 21, 2007.

Simona Nikolova
Nikolova S, Sun Z, Bellyou M, Bartha R. Comparison of T2 and LASER T2dagger image contrast in a rat model of acute cerebral ischemia. Magn Reson Imaging. 2008 Apr;26(3):323-9. Epub 2007 Dec 3.

Li G, Nikolova S, Bartha R. Registration of in vivo magnetic resonance T1-weighted brain images to triphenyltetrazolium chloride stained sections in small animals. J Neurosci Methods. 2006 Sep 30;156(1-2):368-75. Epub 2006 May 8.

Nikolova S, Bowen CV, Bartha R. Experimental validation of a T2rho transverse relaxation model using LASER and CPMG acquisitions. J Magn Reson. 2006 Jul;181(1):35-44. Epub 2006 Apr 17.

Nikolova S, Hughes S, Bartha R. T(2) (dagger) measurement during acute cerebral ischemia by Carr-Purcell MRI at 4T. Magnetic Resonance in Medicine. 2005 Dec;54(6):1448-54.

Donna Padavan
Wan WK, Yang L, Padavan DT. Use of degradable and nondegradable nanomaterials for controlled release. Nanomedicine. 2007 Aug;2(4):483-509. Review.

Puskas, J., Chen, Y., Dahman, Y., Padavan, D. (August 2004). Polyisobutylene-Based Biomaterials. Journal of Polymer Science Part A: Polymer Chemistry. Vol. 42, Issue 13, 3091-3109.

Brian Patenaude
Patenaude B, Smith SM, Jenkinson M. A Bayesian Cost Function Applied to Model-Based Registration of Sub-cortical Brain Structures. WBIR 2006: 9-17.

Babalola KO, Cootes TF, Patenaude B, Rao A, Jenkinson M. Comparing the Similarity of Statistical Shape Models Using the Bhattacharya Metric. MICCAI (1) 2006: 142-150.

Rebecca Pollex
Al-Attar SA, Pollex RL, Ban MR, Young TK, Bjerregaard P, Anand SS, Yusuf S, Zinman B, Harris SB, Hanley AJ, Connelly PW, Huff MW, Hegele RA. Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample. Cardiovasc Diabetol. 2008 Mar 13;7:5.

Wang J, Ban MR, Kennedy BA, Anand S, Yusuf S, Huff MW, Pollex RL, Hegele RA. APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia. Nat Clin Pract Cardiovasc Med. 2008 Sep 9. [Epub ahead of print]

Wang J, Ban MR, Zou GY, Cao H, Lin T, Kennedy BA, Anand S, Yusuf S, Huff MW, Pollex RL, Hegele RA. Polygenic determinants of severe hypertriglyceridemia. Hum Mol Genet. 2008 Sep 15;17(18):2894-9. Epub 2008 Jul 1.

Zamel R, Khan R, Pollex RL, Hegele RA. Abetalipoproteinemia: two case reports and literature review. Orphanet J Rare Dis. 2008 Jul 8;3:19. Review.

Pollex RL, Joy TR, Hegele RA. Emerging antidyslipidemic drugs. Expert Opin Emerg Drugs. 2008 Jun;13(2):363-81. Review.

Pollex RL, Ban MR, Young TK, Bjerregaard P, Anand SS, Yusuf S, Zinman B, Harris SB, Hanley AJ, Connelly PW, Huff MW, Hegele RA. Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample. BMC Med Genet. 2007 Dec 20;8:80.

Pollex RL, Hegele RA. Genetic determinants of plasma lipoproteins. Nat Clin Pract Cardiovasc Med. 2007 Nov;4(11):600-9. Review.

Wang J, Cao H, Ban MR, Kennedy BA, Zhu S, Anand S, Yusuf S, Pollex RL, Hegele RA. Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650). Arterioscler Thromb Vasc Biol. 2007 Nov;27(11):2450-5. Epub 2007 Aug 23.

Pollex RL, Hegele RA: Copy number variation in the human genome and its implications for cardiovascular disease. Circulation. 2007, 115(24):3130-8.

Hegele RA, Pollex RL: Apolipoprotein A-V genetic variation and plasma lipoprotein response to fibrates. Arterioscler Thromb Vasc Biol. 2007, 27(6):1224-7.

Oh J, Ban MR, Miskie BA, Pollex RL, Hegele RA: Genetic determinants of statin intolerance. Lipids Health Dis. 2007, 6:7.

Pollex RL, Hegele RA: Genomic copy number variation and its potential role in lipoprotein and metabolic phenotypes. Curr Opin Lipidol. 2007, 18(2):174-80.7.

Al-Attar SA, Pollex RL, Robinson JF, Miskie BA, Walcarius R, Little CH, Rutt BK, Hegele RA: Quantitative and qualitative differences in subcutaneous adipose tissue stores across lipodystrophy types shown by magnetic resonance imaging. BMC Med Imaging. 2007, 7:3.

Pollex RL, Mamakeesick M, Zinman B, Harris SB, Hegele RA, Hanley AJG: Peroxisome proliferator-activated receptor ã polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes. J Diabetes Complications. 2007, 21(3):166-71.

Huff MW, Pollex RL, Hegele RA. NPC1L1: evolution from pharmacological target to physiological sterol transporter. Arteriosclerosis, Thrombosis, & Vascular Biology. 2006 Nov;26(11):2433-8. Epub 2006 Sep 14.

Al-Attar SA, Pollex RL, Robinson JF, Miskie BA, Walcarius R, Rutt BK, Hegele RA. Semi-automated segmentation and quantification of adipose tissue in calf and thigh by MRI: a preliminary study in patients with monogenic metabolic syndrome. BMC Med Imaging. 2006 Aug 31;6:11.

Pollex RL, Hegele RA. Genetic determinants of the metabolic syndrome. Nature Clinical Practice: Cardiovascular Medicine. 2006 Sep;3(9):482-9.

Pollex RL, Al-Shali KZ, House AA, Spence JD, Fenster A, Mamakeesick M, Zinman B, Harris SB, Hanley AJ, Hegele RA. Relationship of the metabolic syndrome to carotid ultrasound traits. Cardiovascular Ultrasound. 2006 Jul 7;4:28.

Pollex RL, Hegele RA. Longitudinal differences in familial combined hyperlipidemia quantitative trait loci. Arteriosclerosis, Thrombosis, & Vascular Biology. 2006 Jun;26(6):e120.

Pollex RL, Hegele RA. Genetic determinants of carotid ultrasound traits. Current Atherosclerosis Reports. 2006 May;8(3):206-15.

Pollex RL, Mamakeesick M, Zinman B, Harris SB, Hanley AJ, Hegele RA. Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes. Cardiovascular Diabetology, 2005 Nov 7;4:17.

Pollex RL, Hanley, AJ, Zinman B, Harris SB, Hegele RA. Clinical and genetic associations with hypertriglyceridemic waist in a Canadian aboriginal population. Int J Obes (Lond). 2006 Mar;30(3):484-91.

Pollex RL, Hanley AJ, Zinman B, Harris SB, Khan HM, Hegele RA. Synergism between mutant HNF1A and the metabolic syndrome in Oji-Cree Type 2 diabetes. Diabet Med. 2005 Nov;22(11):1510-5.

Pollex RL, Spence JD, House AA, Fenster A, Hanley AJ, Zinman B, Harris SB, Hegele RA. A comparison of ultrasound measurements to assess carotid atherosclerosis development in subjects with and without type 2 diabetes. Cardiovasc Ultrasound. 2005 Jun 15;3:15.

Pollex RL, Hegele RA. Complex trait locus linkage mapping in atherosclerosis: time to take a step back before moving forward? Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1541-4. Epub 2005 Jun 9.

Hegele RA, Pollex RL. Genetic and physiological insights into the metabolic syndrome.
Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R663-9. Review.

Pollex RL, Hanley AJ, Zinman B, Harris SB, Khan HM, Hegele RA. Metabolic syndrome in aboriginal Canadians: Prevalence and genetic associations. Atherosclerosis. 2005 Apr 30; [Epub ahead of print]

Pollex RL, Hegele RA. Hutchinson-Gilford progeria syndrome. Clin Genet. 2004 Nov;66(5):375-81. Review.

Pollex RL, Khan HM, Connelly PW, Young TK, Hegele RA. The metabolic syndrome in Inuit. Diabetes Care. 2004 Jun;27(6):1517-8.

Shahryar Rahnamayan
Rahnamayan S, Tizhoosh HR, Salama MMA. A novel population initialization method for accelerating evolutionary algorithms. Computers and Mathematics with Applications, v 53, n 10, May, 2007, p 1605-1614.

S. Rahnamayan, H.R. Tizhoosh, M.M.A. Salama, Learning Robust Object Segmentation from User-Prepared Samples, WSEAS Transactions on Computers, Issue 9, Volume 4, Sep. 2005, p.p. 1163-1170, ISSN: 1109-2750

S. Rahnamayan, H.R. Tizhoosh, M.M.A. Salama, Towards Incomplete Object Recognition, WSEAS Transactions on Systems, Issue 10, Volume 4, October 2005, p.p. 1725-1732, ISSN: 1109-2777

S. Rahnamayan, H.R. Tizhoosh, M.M.A. Salama, Automated snake initialization for the segmentation of the prostate in ultrasound images. Lecture Notes in Computer Science (including subseries bseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), v 3656 LNCS, 2005, p 930-937.

Syed Raihan
Young B, Raihan S, Ladak H, Kelly M. Rhythmic artifact of physiotherapy (RAP) in ICU EEG recordings. The Canadian Journal of Neurological Sciences Vol 33 (Suppl 1):S26, 2006.

Silvia Riccio
Riccio SA, House AA, Spence JD, Fenster A, Parraga G. Carotid ultrasound phenotypes in vulnerable populations. Cardiovasc Ultrasound. 2006 Nov 13;4:44.

Raphael Ronen
Ronen RR, Clarke SE, Hammond RR, Rutt BK. Carotid plaque classification: defining the certainty with which plaque components can be differentiated. Magn Reson Med. 2007 May;57(5):874-80.

Ronen RR, Clarke SE, Hammond RR, Rutt BK. Resolution and SNR effects on carotid plaque classification. Magn Reson Med. 2006 Aug;56(2):290-5.

Manale Saikaly
Cool DW, Gardi L, Romagnoli C, Saikaly M, Izawa JI, Fenster A. Temporal-based needle segmentation algorithm for transrectal ultrasound prostate biopsy procedures. Med Phys. 37(4): 1660-73, Apr 2010.

Jeffrey Scott
Scott JR, Chin BY, Bilban MH, Otterbein LE. Restoring HOmeostasis: is heme oxygenase-1 ready for the clinic? Trends Pharmacol Sci. 2007 May;28(5):200-5.

Scott, J.R., Gray D.K., Bihari A., Badhwar A., Zhang X., Shan P.Y., Lee P.J., Chakrabarti S., Harris K.A., Potter R.F. Heme oxygenase modulates small intestine leukocyte adhesion following hindlimb ischemia/reperfusion by regulating the expression of ICAM-1. Crit Care Med 2005 Nov; 33(11): 2563-70

Ott, M.C., Scott, J.R., Bihari A., Gray D.K., Harris K.A., Potter R.F. Inhaled carbon monoxide alters liver microcirculatory deficits and inflammation following hindlimb ischemia/reperfusion. FASEB J. Epub 2004 Oct 28.

Ott MC, Scott JR, Bihari A, Badhwar A, Otterbein LE, Gray DK, Harris KA, Potter RF. Inhalation of carbon monoxide prevents liver injury and inflammation following hindlimb ischemia/reperfusion. FASEB J. 2005 Jan;19(1):106-8. Epub 2004 Oct 28.

Badhwar A., Forbes T.L., Lovell M.B., Dungey A.A., McCarter S.D., Scott J.R., DeRose G., Harris K.A., Potter R.F. Chronic lower extremity ischemia: a human model of ischemic tolerance. Canadian Journal of Surgery 2004; 47(5):352-8.

McCarter S.D., Akyea T., Lu X., Bihari A., Scott J.R., Badhwar A., Dungey A.A., Harris K.A., Feng Q., Potter R.F. Endogenous heme oxygenase induction is a critical mechanism attenuating apoptosis and restoring microvascular perfusion following limb ischemia/reperfusion. Surgery 2004; 136(1):67-75.

Wunder C., Scott J.R., Lush C.W., Brock R.W., Bihari A., Harris K.A., Eichelbronner O., Potter R.F., Heme oxygenase modulates hepatic leukocyte sequestration via changes in sinusoidal tone in systemic inflammation in mice. Microvasc Res. 2004 Jul;68(1):20-9.

Badhwar A., Bihari A., Dungey A.A., Scott J.R., Albion C.D., Forbes T.L., Harris K.A., Potter R.F. The upregulation of cytoprotective proteins during ischemic tolerance. Free Radical Bio Med 2004 36(3):371-379.

McCarter S.D., Scott J.R., Lee P.J., Zhang X., Choi A., McLean C.A., Badhwar A., Dungey A.A., Bihari A., Harris K.A., Potter R.F. Co-transfection of heme oxygenase-1 prevents the acute inflammation elicited by a second adenovirus. Gene Therapy. 2003;10(19):1629-35.

Badhwar A., Dungey A.A., Harris K.A., Scott J.A., McCarter S.D., Scott J.R., Forbes T.L., Potter R.F. Limitations of ischemic tolerance in oxidative skeletal muscle: perfusion versus tissue protection. Journal of Surgical Research 109, 62-67 (2003).

Scott, J.R. and Fox-Robichaud, A.E. Hepatic leukocyte recruitment in a model of acute colitis. American Journal Physiol Gastrointest Liver Physiol 2002 Sep;283(3):G561-G566.

Theodore Small
Small TW, Penalva LO, Pickering JG. Vascular biology and the sex of flies: regulation of vascular smooth muscle cell proliferation by wilms' tumor 1-associating protein. Trends Cardiovasc Medicine. 2007; 17(7):230-4.

Small TW, Bolender Z, Bueno C, O'Neil C, Nong Z, Rushlow W, Rajakumar N, Kandel C, Strong J, Madrenas J, Pickering JG. Wilms' tumor 1-associating protein regulates the proliferation of vascular smooth muscle cells. Circulation Research. 2006 Dec 8;99(12):1338-46.

Errol Stewart
Stewart EE, Chen X, Hadway J, Lee TY. Correlation between hepatic tumor blood flow and glucose utilization in a rabbit liver tumor model. Radiology. 2006 Jun;239(3):740-50. Epub 2006 Apr 18.

Lee T-Y, Purdie, TG, Stewart EE. CT Imaging of Angiogenesis. The Quarterly Journal of Nuclear Medicine: 2003 Sep; 47(3): 171-87. Review.

Jesse Tanguay
Tanguay J, Kim HK, Cunningham IA. The role of x-ray Swank factor in energy-resolving photon-counting imaging. Med Phys. 2010 Dec;37(12):6205-11.

Guy-Anne Turgeon
Guy-Anne Turgeon, Glen Lehmann, Gérard Guiraudon, Maria Drangova, David Holdsworth and Terry Peters. 2D-3D registration of coronary angiograms for cardiac procedure planning and guidance. Medical Physics. 2005 Dec;32(12):3737-49

Eranga Ukwatta
Ukwatta E, Awad J, Ward AD, Buchanan D, Samarabandu J, Parraga G, Fenster A. Three-dimensional ultrasound of carotid atherosclerosis: semi-automated segmentation using a level set-based method. Med Phys. 2011 May;38(5):2479-93.

Zheng Wang
Menon DV, Wang Z, Fadel PJ, Arbique D, Leonard D, Li JL, Victor RG, Vongpatanasin W. Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. J Am Coll Cardiol. 2007 Aug 14;50(7):626-33. Epub 2007 Jul 30.

Wang Z, Hughes S, Dayasundara S, Menon RS. Theoretical and experimental optimization of laser speckle contrast imaging for high specificity to brain microcirculation. J Cereb Blood Flow Metab. 2007 Feb;27(2):258-69. Epub 2006 Jun 28.

Zheng Wang, Sarah Hughes, Sudath Dayasundara, and Ravi S. Menon. Theoretical and experimental optimization of laser speckle contrast imaging for high specificity to assess brain microcirculation. Journal of Cerebral Blood Flow & Metabolism, 2006, June 28, advance online.

Mirsattari SM, Wang Z, Ives JR, Bihari F, Leung LS, Bartha R, and Menon RS. Linear aspects of transformation from interictal epileptic discharges to BOLD fMRI signals in an animal model of occipital epilepsy. NeuroImage, 2006, 30(4): 1133-1148.

Mirsattari SM, Bihari F, Leung LS, Menon RS, Wang Z, Ives JR, and Bartha R. Physiological monitoring of small animals during magnetic resonance imaging. Journal of Neuroscience Methods, 2005, 144:207-213.

Qian Liu, Zheng Wang, and Qingming Luo. Temporal clustering analysis of cerebral blood flow activation maps measured by laser speckle contrast imaging. Journal of Biomedical Optics, 2005, 10(2): 24019-1.

Andrew Wiles
Wiles AD, Likholyot A, Frantz DD, Peters TM. A statistical model for point-based target registration error with anisotropic fiducial localizer error. IEEE Trans Med Imaging. 2008 Mar;27(3):378-90.

Linte CA, Moore J, Wiles AD, Wedlake C, Peters TM. Virtual reality-enhanced ultrasound guidance: A novel technique for intracardiac interventions. Comput Aided Surg. 2008 Mar;13(2):82-94.

Wiles AD, Peters TM. Improved statistical TRE model when using a reference frame. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2007;10(Pt 1):442-9.

Moore J, Guiraudon G, Jones D, Hill N, Wiles A, Bainbridge D, Wedlake C, Peters T. 2D ultrasound augmented by virtual tools for guidance of interventional procedures. Stud Health Technol Inform. 2007;125:322-7.

Kevin Wilson
Wilson K., Guiradon G., Jones D., Peters T.: “4D Shape Registration For Dynamic Electrophysiological Cardiac Mapping”. MICCAI 2006, LNCS 4191, pp. 520-527, 2006

Qianren Xu
Q. Xu, M. Kamel, M. M. A. Salama, "A spatially adaptive filter reducing arc stripe noise for sector scan medical ultrasound imaging". Lecture Notes in Computer Science, vol. 3212, pp. 25-32, 2004

Q. Xu, M. Kamel, M. M. A. Salama, "Significance test for feature subset selection on image recognition". Lecture Notes in Computer Science, vol. 3211, pp. 244-252, 2004

Refereed Proceedings:

Kimberly Blackwood
Blackwood KJ, Stodilka RZ, Prato FS. Imaging regenerative therapy with hybrid technology: restoring broken hearts. Interactions. 2006;52(4): 141-155.

 A. Fenster and B. Chiu, "Evaluation of segmentation algorithms for medical imaging," in Proc. 27th Int. Conf. IEEE/EMBS, 2005, pp. 7186-7189.

Bernard Chiu
B. Chiu, M. Egger, J. D. Spence, G. Parraga and A. Fenster, "Quantification of carotid vessel atherosclerosis," in Proc. SPIE Vol. 6143, 2006, 61430B.

B. Chiu, M. Egger, J. D. Spence, G. Parraga and A. Fenster, "Quantification of progression and regression of carotid vessel atherosclerosis using 3D ultrasound images," in Proc. 28th Int. Conf. IEEE/EMBS, 2006, pp. 3819-3822.

N. D. Nanayakkara, B. Chiu, A. Samani, J. D. Spence, J. Samarabandu and A. Fenster, A non-rigid image registration technique for 3D ultrasound carotid images using a “Twisting and bending” model, in Proc. 28th Int. Conf. IEEE/EMBS, 2006, pp. 2738-2741.

Matthew Ford
Ford, M.D., Stuhne G.R., Nikolov H.N., Lownie S.P., Holdsworth D.W., Steinman D.A.(2005). Virtual angiography for visualization and validation of computational fluid dynamics models of aneurysm hemodynamics. Proceedings of the SPIE - The International Society for Optical Engineering, v 5744, n 1, 2005, p 329-37

Ford MD, Nikolov H, Milner JS, Kalata W, Loth F, Lownie SP, Holdsworth DW, Steinman DA. In vitro validation of an image-based CFD model of an anatomically realistic cerebral aneurysm. Proceedings of the 2005 Summer Bioengineering Conference, v 2005, Proceedings of the 2005 Summer Bioengineering Conference, 2005 SBC, 2005, p 1210-1211.

Renee Korol
Canham, P.B., Korol, R.M., Hammond, R., Lucas, A.R., Holdsworth, D.W., Ferguson, G.G. Human brain arteries and aneurysms: collagen organization related to wall mechanics. Invited publication associated with IUTAM Conference, Graz, Austria. May 2005.

Korol, R.M., Canham, P.B., Finlay, H.M., Hammond, R.R., Quantz, M., Ferguson, G.G., Liu, L.Y., and A.R. Lucas. Optical Detection of Structural Changes in Human Carotid Atherosclerotic Plaque. Diagnostic Optical Spectroscopy in Biomedicine III, Proceedings of SPIE, June 2005.

Cristian Linte
Peters TM, Linte CA, Wiles AD, Hill N, Moore J, Wedlake C, Jones D, Bainbridge D, Guiraudon G. Development of an augmented reality approach for closed intracardiac interventions. 2007 4th IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 07EX1544C), 2007, p 1004-7.

Linte CA, Wiles AD, Hill N, Moore J, Wedlake C, Guiraudon G, Jones D, Bainbridge D, Peters TM. An augmented reality environment for image-guidance of off-pump mitral valve implantation. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v 6509, n PART 1, Medical Imaging 2007: Visualization and Image-Guided Procedures, 2007, p 65090N.

Linte CA, Wierzbicki M, Aladl U, Peters TM, Samani A. Towards a biomechanical-based method for assessing myocardial tissue viability. Conf Proc IEEE Eng Med Biol Soc. 2006;1:2884-7.

Linte CA, Peters TM, Samani A. A method for myocardial contraction force reconstruction for tissue viability assessment. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v 6143 II, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 2006, p 61432O.

Donna Padavan
Padavan D.T. and Wan W.K. (March 2007). ‘Synthesis of Novel Versatile Poly(amic acid) Systems For Cardiovascular Applications’. Proceedings of Canadian Biomaterials Society, London, ON.

Padavan D.T., Boughner D. and Wan W.K. (March 2006). ‘Degradable Polymers For Cardiovascular Devices’. Proceedings of Canadian Biomaterials Society, Calgary, AB.

Shahryar Rahnamyan
Rahnamayan S, Tizhoosh HR, Salama MMA. Opposition-based differential evolution for optimization of noisy problems. 2006 IEEE Congress on Evolutionary Computation, CEC 2006, 2006, p 1865-1872.

Yogesh Thakur
Thakur Y, Cakiroglu J, Holdsworth DW, Drangova, M. A device for real-time measurement of catheter-motion and input to a catheter navigation system. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v 6509, n PART 1, Medical Imaging 2007: Visualization and Image-Guided Procedures, 2007, p 65090G.

Andrew Wiles
Wiles AD, Wedlake C, Linte CA, Bainbridge D, Jones DL, Peters TM. Navigation accuracy for an intracardiac procedure using ultrasound enhanced virtual reality. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v 6509, n PART 1, Medical Imaging 2007: Visualization and Image-Guided Procedures, 2007, p 65090W.

Non-Refereed Publications:

Khalid Al-Shali
Al-Shali K, Hegele R. Management of severe hypertriglyceridemia in pregnancy. University of Western Ontario Medical Journal. 2003; 72(2):12-14.

Leonardo Millon
Millon, L. E., (2004) The Aortic Heart Valve – Its Working and the Design and Construction of its Replacement. Workshop presented for the Canadian Medical Hall of Fame series, at the department of Chemical and Biochemical Engineering, London, Ontario, May 28, 2004.

Millon, L. E. (2005) Procedures for Uniaxial Mechanical Testing of Soft Biomaterials using INSTRON 8872 Servohydraulic System. Technical report describing the testing procedure for soft polymers and tissues.

Millon, L. E., Wan, W. K., (2003) Procedures for Uniaxial Mechanical Testing of Soft Biomaterials using INSTRON 8872 and MTS 858 Hydraulic Systems. Technical report describing the testing procedure for soft polymers and tissues.

Qianren Xu
Q. Xu, M. Kamel, M.M.A. Salama, September 2004, “Significance Test for Feature Subset Selection on Image Recognition”, Lecture Notes in Computer Science, Vol. 3211, pp. 244-252.

Q. Xu, M. Kamel, M.M.A. Salama, September 2004,“A spatially adaptive filter reducing arc strip noise for sector scan medical ultrasound imaging”, Lecture Notes in Computer Science, Vol. 3212, pp 25- 32

Book Chapters:

Al-Shali K and Hegele R. Hypertriglyceridemia. In: Encyclopedia of Endocrinology and Endocrine Diseases, Martini L, ed., Academic Press, San Diego, 2004.

Al-Shali K and Hegele R. Neuroacanthocytosis in disorders of lipoprotein metabolism. In: Danek A, ed. Neuroacanthocytosis Syndromes: New Perspectives for the Study of Basal Ganglia Degenerations. Kluwer Academic Publishers, Dordrecht, 2004.

Canham, P.B., Korol, R.M., Finlay, H.M., Hammond, R.R., Holdsworth, D.W., Lucas, A.R. (2006) “Collagen Organization and Biomechanics of the Arteries and Aneurysms of the Human Brain.” In G.A. Holzapfel, & R.W. Ogden (Eds.), Mechanics of Biological Tissue. Berlin, Germany: Springer, 307-322.

DeMont, M.E., Ford, M.D. and Mitchel, S. (2005) Invertebrate locomotion. Encyclopedia of Life Sciences, Nature Online. [Three section manuscript; each author contributed one section]

Peters TM, Moore JT, Guiraudon GM, Jones DL, Bainbridge D, Wiles AD, Linte CA and Wedlake C. Inside the Beating Heart: Toward a Less Invasive Approach to Surgery. International Society of Optical Engineers. SPIE Newsroom. Biomedical Optics & Medical Imaging. Apr. 2007.

Alexandra Lucas, Dana McIvor and Grant McFadden. 2006 Virus-encoded chemokine modulators as novel anti-inflammatory reagents, In Chemokine Biology — Basic Research and Clinical Application Volume I: Immunobiology of Chemokines. Birkhauser, Basel.

Wan, W.K., Hutter, J.L., Millon, L.E., and Guhados, G. (2006) Bacterial cellulose and its nanocomposites for biomedical applications. In: ACS Symposium Series 938, Chapter 15. Cellulose Nanocomposites: Processing, Characterization, and Properties. ACS, Washington, DC. (PhD work)

Canham, P.B., Korol, R.M., Finlay, H.M., Hammond, R.R., Holdsworth, D.W., Lucas, A.R. (2006) “Collagen Organization and Biomechanics of the Arteries and Aneurysms of the Human Brain.” In G.A. Holzapfel, & R.W. Ogden (Eds.), Mechanics of Biological Tissue. Berlin, Germany: Springer, pp.307-322.

Q. Xu, M. Kamel, M.M.A. Salama, September 2004, “Significance Test for Feature Subset Selection on Image Recognition”, Lecture Notes in Computer Science, Vol. 3211, pp. 244-252

Q. Xu, M. Kamel, M.M.A. Salama, September 2004,“A spatially adaptive filter reducing arc strip noise for sector scan medical ultrasound imaging”, Lecture Notes in Computer Science, Vol. 3212, pp 25- 32

Zheng Wang, John R. Ives, and Seyed M. Mirsattari. Simultaneous Electroencephalogram-functional magnetic resonance imaging in neocortical epilepsies. Warren T. Blume (Ed.), Advances in Neurology - Intractable Epilepsies, Vol 97, Chapter 15, pp.129-139, 2006. Lippincott Williams & Wilkins, New York.

Qingming Luo, Haiying Cheng, Zheng Wang, and Valery V. Tuchin. Laser speckle imaging of cerebral blood flow. Valery V. Tuchin (Ed.), Handbook of Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental and Material Science, Vol 1, pp.165-198, 2004. Kluwer Publishers, New York.

Patents:
1. Wan, W. K., L. E. Millon, and H. Mohammadi (2005) Anisotropic Poly(vinyl alcohol) (PVA)-Bacterial Cellulose Nanocomposite. US provisional patent 2005.

2. Wan, W. K., and L. E. Millon. (2005) Poly(vinyl alcohol) (PVA)-Bacterial Cellulose Nanocomposite. US and World patent applications (US No.2005037082-WO No.2005016397). (PhD work)

3. Wan, W. K., L. E. Millon, and H. Mohammadi. (2006) Anisotropic Hydrogels. U.S. and International PCT provisional patent applications (US No.2005/60/666,316-PCT No.2006/000477). (PhD work).