|
Name
|
Department/Graduate
Program
|
Research
Foci
|
|
Aaron
Fenster PhD, FCCPM
Program
Director
|
Tier
I Canada Research Chair in Biomedical Engineering
Director and Scientist, Imaging Research Laboratories, Robarts Research
Institute;
Professor in Radiology, Biomedical Engineering, Medical Biophysics and
Physics (Western). Recipient of the 2007 Premier’s (Ontario) Award
for Innovative Leadership
http://www.robarts.ca/aaron-fenster
|
3D-Ultrasound-guided,
minimally invasive surgery and therapy. Development of 3D
ultrasound imaging systems into clinical use for the quantification
and characterization
of carotid plaque.
|
| Derek
Boughner MD, PhD, FRCPC |
Medicine
(Cardiology); Scientist, Robarts; Professor, Medical Biophysics,
Western
http://www.heartlab.com
|
Heart
valves, heart valve disease and heart valve bioprostheses.
Videodensitometry analysis system developed to quantify and
characterize scar tissue and muscle tissue damage in samples
of heart muscle. Collaboration with Dr. Aaron Fenster generating
three-dimensional images combined with clinical ultrasound
images of the heart. Development of three-dimensional
echocardiography as a diagnostically-useful device in patient
management.
|
| Sean Cregan, PhD |
Associate
Professor, Physiology & Pharmacology,
Western; Robarts Scientist.
http://www.robarts.ca/sean-p-cregan |
Identification
of the molecules that trigger cell
death and loss of brain function in Alzheimer's and Huntingdon's
Disease. Development of drugs to promote cell survival and preserve
brain function. |
| Ian
Cunningham PhD |
Scientist,
Robarts; Professor, Biomedical Engineering, Medical Imaging,
Medical Biophysics
http://www.imaging.robarts.ca/~icunning/
|
Coherent-scatter
computed tomographic imaging, Retrospective ECG-gated cardiac
computed tomography, Linear-systems theory for designing
and assessing x-ray imaging systems.
|
| Maria
Drangova PhD |
Scientist,
Robarts; Associate Professor, Medical Biophysics; Biomedical
Engineering, and Medical Imaging (Western).
http://www.imaging.robarts.ca/~mdrangov/
|
Development
and validation of magnetic resonance imaging techniques for
the diagnosis of cardiac and other vascular diseases. Dynamic
Micro-CT for Pre-clinical Cardiac Imaging. Image-guidance
for Minimally-invasive Cardiac Procedures.
|
| Chris
Ellis PhD |
Professor,
Medical Biophysics at Western; Assistant Dean of Research
(Schulich), Scientist in Vascular Biology at London Health
Sciences Centre/Lawson
Health Research Institute, and Adjunct Professor in Chemical/Biochemical
Engineering, Western.
http://www.uwo.ca/biophysics/people/
chris_ellis.html
|
Oxygen
delivery to tissue by the microvasculature, the role of red
blood cells in regulating oxygen delivery to tissue, remote
microvascular dysfunction observed in sepsis, and the frontier
development of image analysis tools for investigating microvascular
oxygen transport using intravital video microscopy.
|
| Ross
D. Feldman MD, FRCPC, FAC |
Scientist,
Robarts; Professor, Medicine, Pharmacology and Toxicology,
Western; Director
of Clinical Pharmacology, The London Clinical
Trials Research Group; Pharmacologist, Schulich.RW Gunton
Professor of Therapeutics, Western.
|
The
identification of critical regulators of vascular receptor
G-protein mediated mechanisms; The impact of alterations in
this regulatory pathway on vascular resistance;
The mechanisms by which tyrosine kinase activation modulates G-protein
coupled receptor function. Acute vascular effects of aldosterone.
|
| Stephen
S. G. Ferguson PhD |
Scientist,
Robarts; Associate Professor of Physiology, Pharmacology
and Toxicology at UWO. Named
as one of Canada’s Top 40 under 40, is a Tier 1 Canada
Research Chair in Molecular Neurobiology, a Career Investigator
of the Heart and Stroke Foundation of Ontario at Robarts,
and a Professor of Physiology and Pharmacology at Western
|
Research
is on the unravelling of the basic molecular mechanisms underlying
the regulation of G protein-coupled receptor (GPCR) activity.
As a molecular pharmacologist and cell biologist, he studies
the mechanisms underlying the endocytosis and intracellular
trafficking of GPCRs and the role they play in desensitization
and resensitization of receptor responsiveness.
|
| Gerard Guiraudon |
Prof.
Emeritus (Retired Cardiac Surgeon), Surgery; Associate Scientist,
Robarts; Senior Scientist, Dept. of Surgery (Cardiology). |
Image-Guidance
for minimally invasive cardiac procedures; Testing Innovative
Technologies for intracardiac interventions on the closed beating
heart;
Neurogenic substances of atrial fibrillation. |
| Robert
Hegele MD, FRCPC |
Tier
I Canada Research Chair and Director, Blackburn Cardiovascular
Research Laboratory at RRI, Professor of Medicine and Biochemistry
at UWO. |
Genetic
basis of diabetes, atherosclerosis, hyperlipidemia, hypertension
and obesity in Canadian sub-populations and aboriginal communities.
|
| David
Holdsworth PhD |
Scientist,
Robarts, Associate Professor, Medical
Biophysics, Diagnostic Radiology and Nuclear Medicine, UWO
http://www.imaging.robarts.ca/~dholdswo
/index.html
|
Image-guided
interventional therapy for cerebral aneuryms; quantitative
x-ray techniques for peripheral bone densitometry; quantitative
3D analysis of bone mineral density; and investigation of
flow in the stenosed carotid bifurcation using ultrasound.
|
| Murray
Huff PhD |
Director
and Scientist, Vascular Biology Group at RRI; Professor, Biochemistry
and Medicine at UWO.
http://www.robarts.ca/murray-huff |
Relationship
between lipoproteins and atherosclerosis in two main areas:
(i) elucidation of the mechanisms responsible for lipoprotein
over-production and secretion into plasma, and (ii) understanding
the mechanisms responsible for lipoprotein uptake by cells
of the artery wall, leading to one of the early events in
atherogenesis, foam cell formation.
|
| Dwayne Jackson, PhD |
Assistant Professor, Medical
Biophysics, Western.
http://www.microvessels.com/ |
Role of sympathetic nervous system
in modification of cellular and molecular responses in microvessels.
Short-term and long-term role of sympathetic signalling in microvessel
modulation, angiogenesis, cellular mitogenesis, cellular morphology
and cell trafficking. |
| Douglas Jones PhD |
Professor,
Physiology & Pharmacology;
Medicine, Western. Associate Dean, Basic Medical Sciences Academic
Affairs.
http://www.uwo.ca/physpharm/
faculty/jones_doug.html |
Determination
of the physiology and pathophysiology of cardiovascular function.
Recent studies have focused on substrates associated with arrhythmia
in heart failure and atrial fibrillation, mechanisms of, and
development of bioelectric devices for cardiac defibrillation,
and neurophysiological regulatory mechanisms of cardiovascular
control. |
| Mohamed
Kamel PhD |
Professor,
Systems Design Engineering and Electrical & Computer Engineering,
UW. Tier I Canada Research Chair in Cooperative Intelligent
Systems. Director of Pattern Analysis and Machine Intelligence
(PAMI) Laboratory at UW.
http://pami.uwaterloo.ca/kamel.html
|
Computational
intelligence including machine learning, distributed and
multiagent systems, coordination theory and neural networks.
Pattern recognition focused on clustering techniques using
hard, fuzzy and semi-fuzzy approaches. Image processing is
focused on image coding and image enhancement. New methods
for image thresholding, vector quantization and second generation
coding are investigated including adaptive and neural network
approaches.
|
| Bob
Kiaii, MD, FRCPS |
Cardiac
Surgeon, Director of Cardiac Surgery, LHSC; Associate Professor,
Department of Surgery, Western. Director
of the Minimally Invasive Robotic Cardiac Surgery Program
in the Division of Cardiac Surgery at the London Health Sciences
Centre. One of the founding members and an active
scientist at CSTAR.
|
Performance
of ground-breaking robotic-assisted cardiac procedures. Primary
interests are in minimally invasive cardiac surgery
including surgical treatment of atrial fibrillation, mitral
valve procedures, and coronary artery revascularization.
|
| James Lacefield, PhD |
Associate
Professor, Electrical & Computer
Engineering and Medical Biophysics, Western. Ass. Scientist,
Robarts.
http://www.eng.uwo.ca/people/jlacefield/ |
Physical
acoustics and signal processing aspects of biomedical ultrasound
imaging, with an emphasis on
applications of ultrasound to cancer and cardiovascular research. |
| Ting-Yim
Lee PhD FCCPM |
Scientist,
Robarts. Director, PET/CT Research, Lawson Health Research
Institute, SJHC. Professor, Medical Biophysics, and Medical
Imaging, Western. Member of the Clinical Stroke Imaging Network.
http://www.imaging.robarts.ca/~tlee/
|
Acute
stroke imaging using CT; Measurement of myocardial blood
flow using CT to diagnose and treat ischemic heart disease;
Imaging hypoxia in tumours using CT.
|
| Steven
Lownie MD, FRCPC |
Neurosurgeon;
Co-Chair/Co-Chief, Clinical Neurological Sciences, Western.
Associate Professor, Clinical Neurological Sciences;
Associate Scientist, Robarts. |
Three-dimensional x-ray imaging
for vascular disease therapy; Carotid Revascularization Endarterectomy
vs Stenting; Carotid Occlusion. |
| Ian
MacDonald PhD |
Associate
Professor, Department of Medical Biophysics UWO
http://www.uwo.ca/biophysics/people/
ian_macdonald.html
|
Metastasis,
the spread of cancer throughout the body, can be due to the
movement of cells from a primary tumor via the circulation
to other sites. Fortunately, very few cells survive to form
secondary tumors and our research group is studying the reason
for this "inefficiency".
|
| Ravi
S. Menon PhD |
Tier
2 Canada Research Chair in Functional and Molecular Imaging;
Scientist, Robarts Research Institute; Professor, Diagnostic
Radiology & Nuclear Medicine, Medical Biophysics, Psychiatry,
at Western. Named one of Canada's Top 20 researchers aged
40 and under.
http://www.imaging.robarts.ca/Faculty/
menon.html
|
Motor
Control, Learning and Timing;
Physiological Noise Propagation and Suppression in Functional MRI;
Biophysical Basis of Functional Magnetic Resonance Imaging;
Radio Frequency Coils For 4 Tesla MRI
|
| Oleg Michailovich, PhD |
Assistant
Professor, Electrical & Computer
Engineering, U. Waterloo. Coordinator of the ECE MEng Program.
. |
Medical image processing, medical
ultrasound imaging, and functional MRI. Image segmentation, vision-based
control systems, and tracking. |
| Jeffery Orchard PhD |
Assistant Professor in Computer
Science, UW. |
The mathematics of image registration,
and medical image reconstruction. |
| Grace Parraga, PhD |
Associate Prof, Medical Biophysics,
Biomedical Engineering, Medical Imaging and Oncology. Robarts
Scientist. |
Medical imaging in chronic lung
diseases such as asthma, chronic obstructive pulmonary disease,
cystic fibrosis and lung cancer, and in the measurement of stroke
risk. |
Terry
M. Peters PhD FCCPM FACPSEM, F. Inst. P.
|
Scientist,
Robarts; Professor, Departments of Diagnostic Radiology & Nuclear
Medicine and Medical Biophysics, Western
http://www.imaging.robarts.ca/igns/
|
MR
Image acquisition for surgical guidance;
Image-guided Neurosurgery (IGNS);
Image-guidance
for minimally invasive cardiac surgery;
Stereoscopic Visualization;
Multi-modality imaging for IGNS;
Integration of stereoscopic video with IGNS;
Ultrasound Guidance for Neurosurgery;
Accuracy issues in IGNS;
Integration of EEG maps with IGNS.
|
| Geoff
Pickering MD, FRCPC, PhD |
Director,
Krembil Centre for Stem Cell Biology; Scientist, Robarts; Faculty
of Medicine
Department of Medical Biophysics
University of Western Ontario |
Identification
of pathways by which muscle cells contribute to vascular
disease and the field of smooth muscle cell motility and
interactions with the extracellular matrix and has developed
novel theories to explain how smooth muscle cells navigate
through the diseased artery wall.
|
| Tamie Poepping, PhD |
Assistant Professor, Physics
and Astronomy, Western. |
|
| Frank
Prato |
Imaging
Program Leader, Lawson Health Research Institute; Professor
and Chair, Division of Imaging Sciences, Department of Diagnostic
Radiology and Nuclear Medicine, UWO
http://www.uwo.ca/biophysics/
people/frank_prato.html
|
Nuclear
medicine, brain spect, magnetic resonance imaging, cardiac
MRI, MRI contrast agents, radio-biology, ionising, non-ionising,
bioelectromagnetics, and the
biological effects of extremely low frequency magnetic fields.
|
| Richard
Rankin MD, DMRD FRCPC |
Radiologist, Prof. Medical Imaging |
Flow
in the Stenosed Carotid Bifurcation; Non-Invasive Imaging Biomarkers
for human disease. |
| Kem Rogers PhD |
Assoc.
Dean, Medical Sciences Program. Prof. Anatomy & Cell Biology |
A
tissue engineering approach to bioprosthetic heart valve design;
MR imaging of myeloperoxidase activity; Progression, regression
and evaluation of aortic sclerosis in an animal model. |
| Magdy
M. A. Salama PhD |
Professor
in Electrical & Computer Engineering at the University of
Waterloo.
http://ece.uwaterloo.ca/~www_info/people/
faculty/salama.html
|
Research
work in distribution systems involves application of optimization
and system identification to optimally plan and operate distribution
systems. Specific research areas include, on line control
of reactive power using expert systems, loss minimization
of the distribution system by reconfiguration and efficient
load flow analysis.
|
| David
Spence MD MBA FRCPC |
Neurologist; Prof. Neurology and Clinical
Pharmacology, Director, Stroke Prevention and Atherosclerosis
Research Centre |
Genomewide
associations with extreme phenotypes of atherosclerosis; Development
of advanced carotid MRI; Subclinical hypothyroidism and carotid
atherosclerosis. |
| Robert Stodilka, PhD |
Assistant Professor,
Medical Imaging, and Medical Biophysics, Western. Scientist,
Lawson Imaging.
http://www.lawsonimaging.ca/imaging/user/5 |
Imaging
processing with application to nuclear medicine and molecular
imaging; Parametric imaging in nuclear medicine and magnetic
resonance imaging; Applications of nuclear medicine to neurologic
and cardiac disease diagnosis and therapy monitoring, and 3
D in the vivo cell tracking. |
| Wankei Wan, PhD |
Professor,
Chemical & Biochemical
Engineering, Western.
http://www.eng.uwo.ca/research/
compendium/faculty/wwan.htm |
Biomaterials, nanomaterials and medical devices.development
of degradable and non-degradable biomaterials for cardiovascular
devices, novel wound dressings and controlled release. |
| James
A. White MD, FRCPC |
Cardiologist,
London Health Sciences Centre, and Assistant Professor in the
Dept of Medicine at Western. |
Heading
the development of a new clinical research program in advanced
cardiovascular imaging in London, Ontario particularly in myocardial
diagnosis and therapeutics. |
| Tim
Wilson, PhD |
Assistant
Professor, Anatomy and Cell Biology, Director of the Anatatorium,
Western. |
MR-based 3-dimensional computer models of
the anatomy and vascular system. Virtual cerbral ventricular
system. |
