CIHR Project Grant recipients announced

News

January 23 - The Canadian Institutes of Health Research (CIHR) announced more than $11.9 million in research funding through their project grants competition for 17 projects across Western University.

At the Schulich School of Medicine & Dentistry, 15 projects received funding, including four projects at Robarts Research Institute.

“It is great to see the success of the School in this year’s CIHR Project Grants competition,” said David Litchfield, PhD, Vice Dean of Research and Innovation at Schulich Medicine & Dentistry. “These diverse, collaborative research projects will lay the foundation for future success.”

Litchfield also says the School’s success rate for the competition has doubled since last year and highlighted that a variety of investigators at various stages in their careers receiving funding.

Projects that received funding include a mix of both clinical and basic science research, ranging from a study on sensory processing impairments in autism, to examining impaired healing in osteoarthritis, to finding a potential therapeutic target for disc degeneration and back pain.

“The funding that been awarded is a reflection of the research excellence at Schulich Medicine & Dentistry,” said Litchfield.

 

Congratulations to the successful CIHR Project Grant applicants:

Thomas Appleton – Failing to Heal: Impaired Efferocytosis in Osteoarthritis

Samuel Asfaha – Role of DNA methylation in stemness of tuft cells

Timothy Bussey – Interactions between PV interneurons and neuromodulators in cognition relevant to schizophrenia

Lina Dagnino – Epidermal progenitor cell self-renewal and wound healing

Rodney DeKoter – Mechanisms of driver mutation cooperativity in precursor B cell acute lymphoblastic leukemia

Neil Duggal – The Role of Neural Plasticity in Rehabilitation for Reversible Spinal Cord Compression in Elderly Patients

Jason Gilliland (Faculty of Social Sciences and cross appointed to Schulich Medicine & Dentistry) – Examining the influence of a school travel planning intervention on children’s travel behaviour, physical activity, and exposure to pollution around their schools

David Heinrichs – A role for the regulator of purine biosynthesis at the host-pathogen interface

David Hess – Formation of an islet regenerative niche using human mesenchymal stem cell secreted signals

Patrick Lajoie – Cellular responses to protein misfolding in a yeast model of aging

Caroline Schild-Poulter – Tumour-suppressive regulation of the Wnt/ß-catenin signaling pathway by the CTLH complex

Susanne Schmid – Sensory processing impairments in autism

Cheryle Seguin – Disc degeneration, back pain and obesity: PPARdelta as a potential therapeutic target

David Spence – Metabolic and Metagenomic effects of repopulation of the intestinal microbiome in patients with severe unexplained atherosclerosis

Zhu-Xu Zhang – TLR3 is an endogenous sensor of cell death and a potential target for induction of long-term heart transplant survival

 

Congratulations to the CIHR Priority Announcement recipients:

Subrata Chakrabarti – Novel mechanisms in diabetic cardiomyopathy

Elizabeth Gillies (Faculty of Science), and Co-Applicant Frank Beier – Intra-articular Delivery of PPAR-delta Inhibitors for the Treatment of Post-traumatic Osteoarthritis